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KMID : 0376219720090010173
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Chonnam Medical Journal
1972 Volume.9 No. 1 p.173 ~ p.177
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Distribution of R factors in Shigella strains isolated in Korea
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Abstract
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127 strains of Shigella isolated in Korea during the period between 1968 and 1970 were examined for their drug resistances and the distribution pattern of R factors. A majority of the isolates (86.6%) were resistant to one or more of the drugs tested, and 66.4% of these resistant strains were multiply resistant. The most frequently found resistance to each drug was SM (98. 2%), followed by TC (60.9%), CP(44.5%), AP(28.2%), KM(12.7%), and NA(4.5%). When the strains resistances were analyzed according to the pattern, the most commonly encountered were those of SM and TC SM CP.
Of these 110 resistant strains, 61.8% carried R factors, which are transferable by the usual mating process, and 14 kinds of R factor were isolated. The most common R factor was the one which harbored the determinants for TC SM CP resistances, reflecting the frequency of these drugs usage. The highest frequency of transferred resistance to individual drug was CP (93.9% ).
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KEYWORD
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